YouTube star Connor Franta chose: Ennis (Heath Ledger) holding Jack's shirt in Brokeback Mountain; Ryan Gosling and Rachel McAdams kissing in the rain in The Notebook; Elio driving home from the train station in Call Me By Your Name and Cooper (Matthew McConaughey) watching video diaries in Interstellar.
Brokeback Mountain featured multiple times, with many referencing the scene with Ennis holding Jack's shirt, while others also cited Call Me By Your Name scenes.
Twitter user @wrterinthdark shared two animated classics: Mufasa's death in The Lion King and Littlefoot's mother's death in The Land Before Time.
One user shared a moment from the sixth Harry Potter film: "Dumbledore knowing he was going to die and who was going to kill him and not doing anything about it cos it would ruin his long-term plan was the most upsetting scene I've ever seen."
Meanwhile, writer Jenny Johnson shared another memorable contender: Artax the horse getting stuck in the swamp in The NeverEnding Story.