The narrator starts: 'Once you begin to appreciate the structure of the mind, there is no reason to believe that anything about us that can't be changed.
The room soon takes a trippy turn as shots are filtered with hues of cobalt blue, bright green and red as a melodic hum of 'One, two, three, one, two, three' begins bellowing over.
Maniac is a limited series from director Cary Fukunaga, known for Beasts of No Nation and the first season of True Detective.
Jonah stars opposite Stone, Sonoya Mizuno, and Justin Theroux in the series, which was penned by Patrick Somerville.
The show is set to hit the streaming service on September 21, and is based on the Norwegian television series of the same name by Hakon Bast Mossige.
'Set in a world somewhat like our own and similar to our time, Maniac tells the stories of Annie Landsberg (Stone) and Owen Milgrim (Hill), two strangers drawn to the late stages of a mysterious pharmaceutical trial, each for their own reasons,' explains Deadline about the plot.
The pair first worked together on Judd Apartow's 2007 hit comedy Superbad, which saw them play love interests Seth and Jules.
Both have gone on to receive much success in Hollywood since then with Emma winning an Academy Award in 2017 for her role in musical La La Land.
While Jonah himself was recognised by the Academy for his turns in The Wolf of Wall Street and Moneyball, but has failed to win an Oscar yet.
