Picking up decades after the first story, Akeem (Murphy), the Prince of Zamunda, and Semmi return to the US when he discovers he has a son he didn't know about, promising hijinks and laughs.
The 1988 comedy about an African prince who moves to the US in disguise as a poor foreign student to find real love was a huge hit at a time when Murphy was at the top of his movie career.
Murphy was most recently in lauded Netflix biopic Dolemite is My Name, an awards season contender in 2019.
Coming 2 America 2 is the latest production in a long line of movies which have been diverted to streaming after their original theatrical plans were disrupted. Paramount also offloaded the global rights of rom-com The Lovebirds to Netflix at the beginning of the pandemic while Michael B. Jordan movie Tom Clancy's Without Remorse is also said to be shifting to Amazon.
Other films that skipped planned theatrical releases and went straight to streaming include Mulan, The Trial of the Chicago 7, I Am Woman and Artemis Fowl. Pixar's upcoming film Soul will also go direct to Disney+.
This week, Warner Bros announced Wonder Woman 1984 will have a simultaneous cinema and streaming release in the US. In Australia, Wonder Woman 1984 will be released only in cinemas on Boxing Day.