Four years later, the actress reveals that the pair have started to build bridges - thanks to social media.
"Shannen and I talk a lot on Twitter via [direct message]," she told E!.
"And I spoke to her maybe two or three days ago, and we decided that we're going to get together. That date has not been set yet, but yes!"
Milano, 44, said time had softened the edges of their historic feud.
"I think we're just at ages now that what happens 15 years ago, or however long ago that was, it's irrelevant," she admitted.
"I think that what she has gone through, [and] motherhood in my life, I think it just changes people. I'm so happy that she's feeling well. I prayed for her every day that she would feel well and I can't wait to see her."
She's referring to her former co-star's public battle with cancer - Doherty, 46, recently finished chemotherapy after being diagnosed with breast cancer in 2015.
"Cancer, for me, as hard as it is, has been a blessing. It has changed who I am as a human being forever. It's altered my life in ways I can't even speak of," she said in March.