Now a seventh woman, stylist and Bravo reality star Leah Forester, has alleged that Ratner masturbated in front of her over a decade ago in Los Angeles.
"The whole thing was so shocking and it all happened so fast," Forester told The New York Times. "I just remember shaking and being in the bathroom and trying mentally to figure out what to do with this experience that just happened."
She said she struggled for years to come to terms with the alleged incident, and even went to a party for Ratner the next day.
Ratner's lawyers dispute Forester's account, saying Ratner's recollection was "substantially different" and that the two were friendly at the time.
The lawyers also said attending the party the next day "is completely inconsistent with the notion that something objectionable had occurred with my client the day before".
Ratner is the latest Hollywood heavyweight to be accused of sexual misconduct following scandals involving producer Harvey Weinstein, director James Toback, and actors Dustin Hoffman and Kevin Spacey.
Ratner wields considerable power in Hollywood as a successful producer of big-budget action movies. He directed all three Rush Hour films, a franchise that grossed about $US850 million ($1.1 billion) worldwide.
He yesterday ended his relationship with Warner Bros, which was worth $US450 million ($586 million) and was set to end in March 2018.