Cosby could get up to 10 years in prison on each of the three counts of aggravated indecent assault. He is likely to get less than that under state sentencing guidelines, but given his age, even a modest term could mean he will die behind bars.
Constand, 45, a former Temple women's basketball administrator, told jurors that Cosby knocked her out with three blue pills he called "your friends" and then penetrated her with his fingers as she lay immobilised, unable to resist or say no.
It was the only criminal case to arise from a barrage of allegations from more than 60 women who said the former TV star drugged and molested them over a span of five decades.
"The time for the defendant to escape justice is over," prosecutor Stewart Ryan said in his closing argument. "It's finally time for the defendant to dine on the banquet of his own consequences."
Another prosecutor, Kristen Feden, said Cosby was "nothing like the image that he played on TV" as sweater-wearing, wisdom-dispensing father of five Dr Cliff Huxtable on The Cosby Show.
Cosby's retrial took place against the backdrop of #MeToo, the movement against sexual misconduct that has taken down powerful men in rapid succession, among them Harvey Weinstein, Matt Lauer, Kevin Spacey and Senator Al Franken.
The jurors all indicated they were aware of #MeToo but said before the trial they could remain impartial. Cosby's lawyers slammed #MeToo, calling Cosby its victim and likening it to a witch hunt or a lynching.
After failing to win a conviction last year, prosecutors had more courtroom weapons at their disposal for the retrial. The other accusers' testimony helped move the case beyond a he-said, she-said, allowing prosecutors to argue that Cosby was a menace to women long before he met Constand. Only one other accuser was permitted to testify at Cosby's first trial.
Cosby's new defence team, led by Michael Jackson lawyer Tom Mesereau, launched a highly aggressive attack on Constand and the other women.
Their star witness, a longtime Temple employee, testified that Constand once spoke of setting up a prominent person and suing. Constand sued Cosby after prosecutors initially declined to file charges, settling with him for nearly $3.4 million more than a decade ago.
"You're dealing with a pathological liar," Mesereau told the jury.
His colleague on the defence team, Katheen Bliss, derided the other accusers as home-wreckers and suggested they made up their stories in a bid for money and fame. But Cosby himself had long ago confirmed sordid revelations about drugs and extramarital sex.
In a deposition he gave over a decade ago as part of Constand's lawsuit, Cosby acknowledged he had obtained quaaludes to give to women he wanted to have sex with, "the same as a person would say, 'Have a drink'." The sedative was a popular party drug before the US banned it more than 30 years ago.
Cosby also acknowledged giving pills to Constand before their sexual encounter. But he identified them as the over-the-counter cold and allergy medicine Benadryl and insisted they were meant to help her relax.
The entertainer broke racial barriers as the first black actor to star in a network show, I Spy, in the 1960s. He created the top-ranked Cosby Show two decades later. He also found success with his Fat Albert animated TV show and served as pitchman for Jello-O pudding.
Later in his career, he attracted controversy for lecturing about social dysfunction in poor black neighbourhoods, railing against young people stealing things and wearing baggy pants.
Cosby's reputation as a public moralist prompted a federal judge, acting in response to a request from the Associated Press, to unseal portions of the deposition.
Its release helped destroy the Cosby Show star's career and good-guy image. It also prompted authorities to reopen the criminal investigation, and he was charged in late 2015.
The Associated Press does not typically identify people who say they are victims of sexual assault unless they grant permission. Constand has done so.
