Declines in shares of DuPont, last 1.3 per cent weaker, and Caterpillar, last down 1.2 per cent, paced losses in the Dow.
US Treasuries received a boost from the data showing weakness in parts of the American economic recovery. Yields on the benchmark 10-year bond dropped four basis points to 2.97 per cent.
The US Senate is expected to approve Janet Yellen as the next Chairman of the Federal Reserve today. Ben Bernanke's second four-year term expires on Jan. 31.
Shares of Twitter sank, last down 6.1 per cent, after Morgan Stanley downgraded its rating on the stock to underweight.
"As competition for online ad dollars intensifies, we guide investors to Google and Facebook, dominant platforms with more attractive risk/reward," Scott Devitt, an analyst at Morgan Stanley, in a note, according to Bloomberg News. "In our view, success is far from guaranteed at this early stage."
In Europe, the Stoxx 600 Index ended the session with a 0.2 per cent decline from the previous close. The UK's FTSE 100 finished steady, Germany's DAX edged 0.1 per cent lower, while France's CAC 40 fell 0.5 per cent.
A Reuters survey found that Opec's oil output fell in December to the lowest since May 2011. Opec output averaged 29.53 million barrels per day last month, down from 29.64 million barrels per day in November, according to the survey based on shipping data and information from sources at oil companies, Opec and consultants.
"Supply issues are still in the spotlight," Carsten Fritsch, analyst at Commerzbank, told Reuters. "In terms of Libya, it is too early to say if production levels will stabilise further."