"The US is about to celebrate Thanksgiving, which is the second-biggest time of year after Christmas for app store sales.
"If we can hold our position over the weekend, it'll be big for us."
Bloons TD 5 for mobile users comes after the game was first launched on the Ninja Kiwi website late last year.
Harris said that iPad and Android versions of the game would be coming soon.
Ninja Kiwi has produced around 60 games and its TD series itself has had over 1 billion plays on web and mobile devices. Bloons TD 4 has sat in the top 100 of all apps in the US App Store for over two years.
The company makes money from advertising on the Ninja Kiwi games site, by selling virtual currency and from their apps for Android and Apple devices smartphones and tablets.
Founded by brothers Chris and Stephen Harris in 2006, Ninja Kiwi recently acquired Scottish game developer Digital Goldfish.
The merger would allow Ninja Kiwi to better develop mobile versions of its games.
Ninja Kiwi made the 2012 TIN100 Report's "10 Hot Emerging Companies", with revenue growth of 66 per cent over the past year.