The site was like a swimming pool in 2013 but $120 million was invested to regenerate that end of Ponsonby, Chambers said.
"This building will end up with 1200 people working in it," Chambers said of the Cider Building, named after the DYC vinegar factory once there.
Ralph Kemmler, Woolworths property director from Sydney, said the site had been purchased just after the GFC.
"There was not a lot of confidence in the market," Kemmler said. "So we were being counter cyclical".
It was relatively rare for Woolworths to be involved in mixed-use developments like at Ponsonby but he said he was pleased with the result.
Anti caged-egg protestors staged a demonstration outside the opening of the new Countdown.
A supermarket spokesman said up to 80 per cent of eggs being sold by the business were barn or free range.