Police raided two businesses and a home in Sydney on Tuesday as part of an investigation into an alleged fraud that also involved a former supplier.
Thorburn said he was personally personally affected by what he said, if proven, would be a very significant breach of trust.
"I'm hurt because there are people here who are alleged to have been involved that I know who they are and - particularly in one case - I've had a longstanding personal relationship," Thorburn said.
The allegations are that a person received corrupt commissions to authorise inflated invoices sent to the bank by a contractor.
Thorburn said the bank could not put a figure on the amounts of money involved, which detectives believe could total tens of millions of dollars taken over several years.
He said the bank would update investors at its half-year results on May 3.
"In amounts, they're not material for the bank, but they're material for our reputation," Thorburn said.