The Briton and Key are expected to discuss the challenges and opportunities of the 21st century.
The businessman will also take some questions directly from the audience, while Newshub journalist Samantha Hayes will MC the event, with entertainment by the Peter Urlich Swing Quartet.
The event is projected to raise at least $300,000 for Virgin Unite, Branson's global philanthropic effort to create a better world.
The non-profit charity was founded in 2004 and promotes entrepreneurship, business solutions to climate change, creating disruptive collaborations, changing business for good and promoting human dignity.
Branson founded the Virgin Group in 1970, and Forbes currently lists the 66-year-old's wealth at more than NZ$7 billion.
The philanthropist also serves on the Global Commission on Drug Policy and supports ocean conservation with the Ocean Elders.
Those wanting tickets for this month's event, which are being sold from $595+GST, can join a waiting list at www.ducoevents.com.