"Those are the two that have been stunning performers through all this volatility so they're the ones who are ripe for profit taking," Lister said.
A strong lead from the US overnight and some signs the virus outbreak had turned a corner had left investors in an optimistic mood.
"Some of the stocks that are going up in response to that are stocks that had been heavily sold off," Lister said.
F&P Healthcare led the market lower, falling 5.7 per cent to $27. A2 Milk declined 2.5 per cent to $17.48.
Both companies were also affected by a stronger kiwi dollar eroding their export earnings, Lister said. The kiwi rose to 60.14 US cents at 5pm.
Vista Group International, which is also exposed to currency movements, fell 3.8 per cent to $1.01.
Spark New Zealand fell 1.1 per cent to $4.35. Smith said investors probably rotated out of the stock, which is being seen as defensive due to the telco's business continuing through the disruption.
Telecommunications network provider Chorus declined 2.7 per cent to $6.61.
"Data is running high with everyone locked away at home and it will be interesting to see what sort of benefits accrue for the company after lockdown if more people keep working from home." Smith said
While the big names declined, companies that have been hardest hit in the pandemic were stronger.
SkyCity Entertainment Group jumped 9.1 per cent to $2.15, while Air New Zealand advanced 7.8 per cent to 90 cents. Tourism Holding rose 4.6 per cent to $1.15.
Auckland International Airport increased 5.5 per cent to $5.75. The $200m share purchase plan component of its $1.2 billion capital raising opened today.
Metlifecare rose 7.4 per cent to $3.77, bouncing back from yesterday's 17 per cent slide after a $1.49 billion takeover deal collapsed.