"More than rates, the curve shape has been consistent, and telling a strong story," Aaron Kohli, fixed-income strategist in New York at BMO Capital Markets , one of the 23 primary dealers that trade with the Fed, told Bloomberg. "Everyone thinks the Fed will be on hold forever."
The Dow moved lower as slides in shares of American Express and those of IBM, each last down 1 percent and 2.7 per cent, outweighed gains in shares of Apple, trading 3.9 per cent higher recently.
Apple shares touched the highest level this year, amid indications of strong demand for its newly released iPhone 7. Meanwhile, rival Samsung is struggling with a recall of its Galaxy Note 7 phones after incidents of its batteries catching fire while charging.
"With the carriers telling Samsung owners that Samsung wants you to take your phone back into the store, well, people are going to look elsewhere," Longbow Research analyst Shawn Harrison told Reuters.
Monsanto's shares rose after Germany's Bayer agreed to buy the US seeds company in a deal worth about US$66 billion, the largest this year, but investors are concerned about regulatory hurdles.
More than rates, the curve shape has been consistent, and telling a strong story.
Bayer agreed to pay US$128 a share for Monsanto; the Leverkusen-based company first offered US$122 a share in May, then US$125 in July, and raised it to US$127.50 last week.
Closing is expected by the end of 2017, the companies said. Bayer said it agreed to a US$2 billion reverse antitrust break fee, "reaffirming its confidence that it will obtain the necessary regulatory approvals."
Investors aren't as confident. Monsanto shares traded 1 percent higher at US$107.20 as of 1.44pm in New York, after rising as high as US$107.75 earlier in the session. Bayer shares closed 0.7 per cent higher in Frankfurt.
"We expect significant antitrust and political hurdles and assign 50 per cent probability of deal completion," analysts at Sanford C Bernstein & Co said in a note, Bloomberg reported. "The market seems to agree."
In Europe, the Stoxx 600 Index ended the session with a decline of 0.1 per cent from the previous close. Germany's DAX index also slipped 0.1 per cent, while France's CAC 40 index fell 0.4 per cent. the UK's FTSE 100 Index rose 0.1 per cent.