Boeing was dragged lower after saying it would inspect wings for cracks on undelivered 787s, and after a 777 flown by Malaysian Airline System disappeared over the ocean three days ago.
"News of the wing and inspections likely lower first quarter deliveries, plus the 777 aircraft incident in Asia will likely weigh on the Boeing stock this week," Peter Arment, an analyst at Sterne, Agee & Leach, told Bloomberg News.
In Europe, the Stoxx 600 Index ended the session with a 0.5 per cent drop from the previous close. The UK's FTSE 100 fell 0.4 per cent, while Germany's DAX gave up 0.9 per cent. France's CAC 40 added 0.1 per cent.
Concern about the ongoing crisis in Ukraine keeps weighing on markets worldwide.
Meanwhile, Philadelphia Federal Reserve Bank President Charles Plosser reiterated his concern that the US economy might be stronger than policy makers anticipate and suggested the Fed should accelerate the tapering of its monthly bond-buying programme.
On Friday, a report showed American employers added a higher-than-expected 175,000 jobs, while January's jobs gain was revised up. The unemployment rate rose to 6.7 per cent, from 6.6 per cent.
"I expect that the unemployment rate will reach about 6.2 per cent by the end of 2014, and, if anything, that may prove too pessimistic," Plosser said in a speech in Paris. "Given the recent trends, an unemployment rate below 6 per cent is certainly plausible."
"Reducing the pace of asset purchases in measured steps is moving in the right direction, but the pace may leave us well behind the curve if the economy continues to play out according to the FOMC forecasts," Plosser said.