In afternoon trading in New York, the Dow Jones Industrial Average dropped 0.68 per cent, while the Standard & Poor's 500 Index shed 0.34 per cent, and the Nasdaq Composite Index declined 0.58 per cent.
Europe's Stoxx 600 Index finished the session with a 0.3 per cent slide from the previous close. The euro shed 1.1 per cent against the US dollar, and lost 1.6 per cent against the Japanese yen.
Italy's FTSE MIB fell 2.5 per cent. The nation's bank shares dropped, sending those of Intesa Sanpaolo, Banco Popolare and UniCredit more than 5.5 per cent lower.
"The Cyprus deal removed some of the tail risk regarding a messy default and exit from the euro zone, but a dangerous precedent of seizing bank deposits was set and Dijsselbloem's comments solidified concerns about future bailouts," Omer Esiner, chief market analyst at Commonwealth Foreign Exchange in Washington DC, told Reuters.
"A depositor in an Italian or Spanish bank right now is likely to be reconsidering their capital allocations as well as those with counter-party risk in shaky euro zone countries," he said.
Shares of Dell gained, last up 2.9 per cent, after the company said it received proposals from Blackstone Group and Carl Icahn that may be superior to Michael Dell's buyout plan. While they filed separate proposals, Icahn said he was talking with Blackstone about a joint bid.
There also was good news for investors in a 17-year-old British boy who has sold the Summly mobile app he created to Yahoo for at least 20 million pounds. The app provides summaries of news articles for users. Yahoo plans to eliminate the app and incorporate the technology into several of its own products.