In addition, Qantas plans to consolidate its catering business into four centres in Sydney, Melbourne, Brisbane and Perth.
The lease on the current facility in Adelaide will not be renewed when it expires in March 2013, while one centre in Sydney and another in Cairns may be sold.
Its workforce planning team, which are currently dispersed around the country, will also be consolidated in Sydney.
"Job reductions are expected as a result of aircraft retirements and operational changes,'' the airline said.
Qantas will also review its heavy maintenance facilities, with the aim of consolidating its three facilities.
But there were no plans to move operations offshore, chief executive Alan Joyce said.
"With aircraft retirements, there is simply not enough heavy maintenance work to justify the three facilities in Melbourne, Brisbane and Avalon,'' he said.
He said consultations would be held with the relevant unions before a decision was made on the future of the heavy maintenance services.
"But we will be acting in the best interests of the business and our people over the long term,'' Joyce said.
"We will not be propping up the past at the expense of the future.''
- AAP