"Slower growth is the price of structural reform for the longer term," the report said.
China's economy, the world's second biggest, is now expected to expand 7.6 percent, down from 8.2 percent forecast earlier this year.
The country's communist leaders are trying to reverse a painful, extended slowdown that dragged growth down to a two-decade low of 7.5 percent in the second quarter.
In India, growth is slowing because industry and investment are hindered by poor infrastructure and long delays in structural reforms, the bank said in cutting its forecast to 4.7 percent growth from 6 percent.
The bank also lowered its Southeast Asia forecast because of lackluster exports and moderating investment in Indonesia, Thailand and Malaysia, though stronger than expected growth in the Philippines partially offset the decline.
The region growth outlook was also hurt by nervousness that U.S. Federal Reserve policymakers were planning to scale back their monetary stimulus program, the bank said. The worries rocked financial markets in some countries including India and Indonesia, where stocks and currencies tumbled as foreign investors started pulling funds out on the expectation of higher returns back home.
The turbulence triggered fears that it would lead to a wider meltdown similar to the 1997 Asian financial crisis, but the ADB said such fears were "unwarranted" because countries have since beefed up their foreign currency reserves, strengthened economic management and tightened financial regulation and supervision.
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Asian Development Bank: http://www.adb.org