Maggie Varcoe, sister of Australian Rules star Travis Varcoe, has tragically died after sustaining a head injury while playing in a women's grand final in an Adelaide Football League.

Varcoe, playing for club Angle Vale, walked off the field after the devastating collision but later collapsed in the team's dressing room. The 27-year-old was rushed to hospital immediately.

She was in a coma at Royal Adelaide Hospital all week before news broke of her death on Thursday night.

She reportedly spent her final days surrounded by loved ones.