Wafah Dufour, who uses her mother's maiden name, is playing a series of live music shows with her all-girl band in the UK.
Osama bin Laden's niece has been spotted playing live shows with her punk band in London.
Wafah Dufour, who uses her mother's maiden name, is the lead singer of the all-female group, Deep Tan, which also includes French model Melia Beaudoin and Celeste Guinness, an heiress to the Guinness brewing empire.
The band has recently released two new singles, Shimmer and Constant Inconsistencies, and has several shows planned across London and Paris.
They played a gig in Peckham in south London earlier this month and another in Hackney in the city's east on Wednesday.
Dufour, who once dated singer John Legend, says she never met her uncle and does not like to discuss her family.
When she was approached by a journalist from the Daily Mail at the show in Peckham she "politely" declined to discuss bin Laden, the reporter said.
In an interview with GQ magazine in 2005, Dufour said it was tiring having to constantly explain herself.
"I was born in the (United) States, and I want people to know I'm American. I want people here to understand that I'm like anyone in New York. For me, it's home," she said.
"It's really tough that I have to always explain myself. It's like every time I meet someone, I have to move a huge mountain that's in front of me, and sometimes I get tired."
Dufour, 44, was living in New York when her uncle orchestrated the September 11 terror attacks in 2001.
She then moved to London for a few years but was hounded by the press and returned to the United States in 2004 to pursue a career in music.
Her mother, Carmen bin Laden, was married to Osama bin Laden's wealthy older brother, Yeslam, but the couple divorced in 2006 after several years apart.
Carmen wrote about her experiences in the book, Inside the Kingdom: My Life in Saudi Arabia, later telling The Independent: "If we do not speak out, they have won and I don't want them to win".