"Aerial 1080 is the most effective pest control method across large areas and difficult terrain and our monitoring shows it's a very successful way of protecting vulnerable species and allowing birds to produce more chicks to sustain and grow their populations," Ms Barry said.
Department of Conservation senior communications adviser Herb Christophers said the areas would be fully sign-posted and neighbours would be consulted before the operations start.
The application rate was about 1 to 1.5kg of bait per hectare with each bait containing a .015 per cent active ingredient - the rest was cereal bait (porridge), he said.
NZ Deer Stalkers Association president Bill O'Leary said it was opposed to 1080 but understood DoC's commitment to protecting native birds.
The association had negotiated with DoC to reduce its effect by using smaller pellets and dropping 1080 at certain times of the year when more feed was available for deer, he said.
"We also understand there are a lot of people out there who are opposed to the use of toxins."
By the numbers
* 25 million native birds are killed each year by predators like possums, rats and stoats.
* The research shows that use of 1080 in a three-yearly cycle allows the kiwi population to grow at 4 per cent per year.
* Results from long-term monitoring at Tongariro Forest Kiwi Sanctuary in the central North Island show that the survival of kiwi chicks to six months of age doubles in the two years after 1080 use compared to other years.