Security Manager John Nieuwoudt said people use the wheelchairs to take their relatives to their cars when they are discharged from hospital and many do not return the wheelchairs to the hospital.
Some 17 wheelchairs have gone missing from areas in Rotorua Hospital notably from the medical, surgical, orthopaedic and birthing units.
Mr Nieuwoudt said the DHB can not afford to replace as many as it would like and sometimes patients get impatient when they have to wait for a wheelchair to be found.
Lakes DHB staff can also spend quite a lot of time tracking down family members where equipment has been loaned trying to retrieve the equipment. In extreme cases, the matter can be put in the hands of debt collectors.
Several years ago Lakes DHB purchased wheelchairs that can not be collapsed and easily put into the boot of a car but the wheelchairs have continued to go missing. It's thought larger model cars or four wheel drive vehicles can still accommodate an unfolded wheelchair.
Rotorua Hospital is planning to buy six new wheelchairs in the coming year at a cost of $9,000 but said the money could be better spent on other equipment if wheelchairs did not go missing with such regularity.
People who locate hospital equipment and return it to Rotorua Hospital will not face any questions or any action.