HHSOG levelled the scores again about four minutes into the third quarter, but again turned the ball over as they looked to take the lead.
Otane never looked back, extending their advantage to 42-35 by the end of the third quarter.
They put the clamps on in the fourth, keeping Huia scoreless over a four-minute period to lead by as many as 14 points.
A late fightback from HHSOG reduced the deficit to eight, but they had to settle for their first loss of the championship round.
Huia are third on the ladder after Otane and undefeated All In: Elusive, who got their fifth win of the round 54-50 over Central.
Last year's beaten finalists had to battle to stay at the top, with Central holding the lead at the end of the first and second quarters.
Both high school teams in the competition managed to pick up their first wins of the championship round, with Napier Girls' defeating All In: Mavericks 51-41 and Hastings Girls' beating Outkast Sports 50-44.
Next Friday they will face off against each other, while Otane play All In: Mavericks. All In: Elusive play HHSOG: Huia while Central play Outkast.