One person was seriously injured and two people were moderately injured in two separate crashes around Napier.
A police spokeswoman said the first was on Main Rd North, Bayview, and was reported to police at 5.20am.
The spokeswoman said reports indicated the incident involved one vehicle.
A St John spokesperson said they responded at 5.15am and assessed, treated and transported one patient with serious injuries and took them to Hawke's Bay Hospital's emergency department.
The road was blocked for about and hour and a half before re-opening around 6.50am.