"We will be running an outpatients clinic and operating theatre, and will be treating a lot of the common eye diseases such as cataracts, eyelid conditions and glaucoma.
"These are becoming increasingly complex with new interventions coming online in the next few years - but really it's business as usual, just in a different building."
Looking to the future, the pair hoped more ophthalmologists would move to the region in coming years, and that they might be able to accommodate them.
The facility, the building of which was expected to be completed this month, comprised reception area, waiting room, consulting and treatment rooms and an operating theatre.
"This was an empty shell so we have been able to design it how we want it with easy access, ample parking and a covered area for people to be dropped off and picked up at the door," Dr Buller said.
The pair called on the services of Fat Parrot Architecture's Pierre Du Toit to help with the design, as well as the distinctive paintwork.
Mr Du Toit said the Bullers presented him with a large palette of colours, which he whittled down to about 10, and then put together in a striped design, similar to what he had seen on buildings in Europe.
"It was a challenge - we had a bland building without any windows - so far there's been a great, positive reaction to it."
The collaboration continued with the contracting of MCL Construction for the building work, and project manager Phil Mitchell said it had been an interesting project, working with the owner operators and making their ideas come to life.