A St John ambulance spokeswoman said one person sustained moderate injuries and one person sustained serious injuries. Both were transferred to Hawke's Bay Hospital.
At 7.43pm on Saturday fire and emergency services responded to a chimney fire in Onekawa, Napier.
The fire took a little more than an hour to extinguish and a spokesman said the fire had gotten into the roof of the property.
Four fire trucks responded to the fire and there were no injuries reported.