A second serious crash has happened in Hawke's Bay, this one blocking the south bound lane on Pakowhai Road.

A police spokesperson said the crash occurred between Chesterhope Rd and Links Rd.

A spokesperson for St John confirmed three people were injured in the crash, one moderately, and two receiving minor injuries.

All three were transferred to Hawke's Bay Hospital.

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The crash occurred shortly after 6pm. Pakowhai Road had been being used to divert traffic off the expressway due to an earlier crash, although the expressway had re-opened shortly

Motorists are advised to avoid Pakowhai Rd.

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