A boat carrying 30 Cubans is missing en route to the United States.
The 9m launch should have arrived in southern Florida two days ago.
Two planes, a helicopter and a patrol boat from the Coast Guard have been searching for the would-be immigrants, who may have been trying to enter the US with smugglers, the Coast Guard said.
Weather conditions in the Straits of Florida, which separates Cuba and the United States, were unfavourable at the weekend.
Cuban exiles lost at sea
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