A police spokeswoman said one person was reported to have minor to moderate injuries.
She said one lane was partially blocked for a time and traffic may be impacted.
A photographer at the scene saw one person taken away in an ambulance.
A worker at the Great Spice Indian Takeaway on the corner of Te Ngae and Coulter roads said he saw police cars, fire trucks and ambulances heading past.
He believed the crash was about 500 or 600m further down the road towards Rotorua Airport.
A St John Ambulance spokesman confirmed tonight that two people were taken to Rotorua Hospital, one with moderate injuries and the other suffered minor injuries.
