If the council's LAPP is passed, it would mean the four premises in Rotorua with interim licences to sell the products would have them revoked from June 5.
Hearings begin at 9.30am on Thursday in the council chamber.
The Rotorua District Council received 541 submissions to its LAPP.
Of those, 484 were received from a petition to allow retailers to sell the products as a safer alternative.
The majority of the remainder of the submissions opposed having the products available in the community.
Rotorua Mayor Steve Chadwick said MPs responsible for the law would be hearing from the council about the issue in the near future.
She said she felt strongly about a total ban on legal highs due to the detrimental impact they had on the community.
Rotorua police prevention manager Inspector Ed Van Den Broek said police were dealing with synthetic cannabis-related incidences on a regular basis.
"We quite regularly deal with young people who are affected by these drugs, becoming aggressive. Police are called to disorder and fighting which can lead to arrests."
He said police attended family violence incidents where synthetic cannabis was a precursor - either its use or the financial side effects - and it was being used by a cross-section of society.
"Synthetic cannabis is becoming more prevalent and more of a problem for us. Police are supportive of the council and its policy, we see it as a positive step for the city of Rotorua."
WHAT DO YOU THINK? COMMENT BELOW
Rotorua MP Todd McClay said he also supported the council's proposed policy. "I have seen first-hand the harm they [legal highs] cause.
"Previously, there were 20 to 30 shops selling these drugs in our city, following legislation only four remain. These four shops need to listen to our community and take these products off their shelves."
Mr McClay said he was committed to reducing harm in communities and when a means to effectively ban legal highs was found he would vote in favour of it.
"No country in the world has been able to effectively ban synthetic drugs.
"Parliament's legislation has, however, reduced harm significantly. It gives the Ministry of Health and police ability to hold importers, manufacturers and retailers to account.
"I expect that the four remaining stores in Rotorua will lose their interim licences once the council has completed this work and this will be a good result for our community," Mr McClay said.
Waiariki MP Te Ururoa Flavell said he and the Maori Party did not support their sale, either.
"The effects of synthetics are worse than normal cannabis use and can cause adverse hypertension, agitation, vomiting, hallucinations, psychosis, seizures, convulsions and panic attacks.
"We should not be allowing our people to use substances which affect their bodies like this. I would support a complete ban on them if it was proposed.
"However, the problem is that once one product is banned, a new product tends to pop up in its place so it's about finding a solution that takes care of all these possible scenarios."
