The Serious Crash Unit was advised.
Rotorua Fire Brigade senior station officer Tony Kelly said they were joined by the Tirau Volunteer Fire Brigade.
"The collision involved a car turning right towards Mamaku. There were three people trapped across the three different vehicles."
He said they were on the scene for at least an hour and a half.
The road was closed and there were lengthy diversions in place. All motorists travelling between Tirau and Rotorua were diverted through Putaruru and Tokoroa. Police thanked motorists for their patience.
The crash brought the holiday road toll to five.
"It's a bit scary driving on our roads at the moment with the road toll so high," Kelly said.
The Christmas-New Year holiday road period runs until 6am on January 3. Last summer 15 people died on New Zealand roads during the holiday period.
In the past year there have been 373 deaths on our roads compared with 327 the year before.