Ms Meihan said the charity did everything from supporting patients through treatment to helping fund petrol.
"Kerrie and the team work out what needs to be funded and the support is amazing."
She said it was great day last year, with people bringing their kids, pushing prams and riding bikes.
Mitre 10 Mega manager Graeme Ricketts said they were starting to get a lot of registrations but expected more to flood in over the next few days.
"With the good weather forecast I would expect a mad rush leading up to Sunday."
Last year they received almost 1500 registrations so the team hoped to crack the that mark this time.
CanTeen youth co-ordinator Kerrie Waby said support from the event empowers young people with cancer and helps them realise they are not on their own.
In the past six years the fundraiser has raised more than $100,000 for CanTeen.
The event begins at 7.30am with the 28km mega walk and run and ends at 12.30pm with a prizegiving.
The three other categories are a 15km run or walk, 6.5km run or walk, and a 3.5km run or walk.
The entry fees for the event are $20 for adults, $10 for children under 15 and adults over 65, and free for under-5s.
People can also buy a family pass, which is two adults and two children for $40 or teams of four for $40.
Buses to and from the event are $3.
For more information visit mitre10.co.nz and to register go in to either the Hastings or Napier Mitre 10 store or register on the website.