A person is "unaccounted for" following a house fire north of Kaikoura last night, police say.

Tasman Police District spokeswoman Barbara Dunn said Marlborough police are investigating the fire at a house on State Highway 1 at Waipapa Bay, 30 kilometres north of Kaikoura.

The fire was reported about 8.30pm and was fully involved when emergency services arrived, she said.

"One occupant from the house is unaccounted for."

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A scene guard was in place overnight and police and fire service investigators will begin their investigation today.