Dr Bullen led the team's 2013 trial that tested an earlier type of e-cigarette, and found they were safe and as good as nicotine patches for quitting.
The research team has been working closely with the "vaping" community in Auckland to identify the best e-cigarette to test, and has decided on one of the latest "tank" style e-cigarettes.
"We are hoping to recruit around 1800 people across New Zealand into the study." Dr Walker said.
Participants must be willing to be randomly allocated ["like the toss of a coin"] to one of three groups: using nicotine patches alone, using nicotine patches and nicotine-free e-cigarettes or using nicotine patches and e-cigarettes containing nicotine. People will be followed up by phone for six months to see how successful they've been at quitting.
Interested Northlanders who smoke but want to quit, are at least 18 years of age, and have access to a phone, can call 0800 367 644, email ascend-2@auckland.co.nz or go to http://ascend2.nihi.auckland.ac.nz to find out more about what the study involves.