While people spoke of developing an immune response to the flu, such changes meant that while someone may be protected from one strain having already been exposed to it, the immune system may not be able to recognise a new strain, and as such meant it was important to be vaccinated each year, she said.
"If you have had a vaccination in previous years you have some immunity to strains that were in it, but no immunity to what's coming in the new flu season."
She said that while being vaccinated was the best option to prevent getting a flu, other prevention measures such as basic hygiene - coughing and sneezing etiquette, hand washing, and staying at home when sick were also important.
To better track the flu and its severity, the ESR this year launched a new "dashboard", providing a near real-time measure of the impact of the flu through the season, and to help the health sector manage it.
While it was aimed at health professionals, it would also provide a guide to members of the public, Dr Oakley said.
"The new system will also be extremely useful in the event of a flu pandemic.
"Multiple flu viruses circulate in a season; some are worse than others, some parts of the community are more vulnerable, and in some years a flu virus is worse than previously experienced."
With this year's flu season just beginning, Dr Oakley said the up-to-date information provided on the ESR website would be of great value.