Second unbeaten side Taradale have home advantage in a local derby against Napier Pirate, who won last year's semifinal between the two clubs before going on to win the final.
A Taradale win will put Pirate at risk of missing out on this year's top four.
Havelock North also have home advantage against Tamatea, who reckon they always go well against the villagers but will need to go even better if they are to stop their Premier-grade losing streak hitting 60 matches, while, like Havelock North, Clive need a win over Tech at Clive to keep their slim playoff hopes alive.
Havelock North will be hoping for a winning effort to celebrate wing Shannan Chase's 50th Premier match for the club, having possibly just one more before Magpies Mitre 10 Cup squad members are siphoned out of club rugby from the following weekend.
In the remaining match in Flaxmere, MAC and Central will looking for the points to avoid the threat of relegation, unlikely as it is with no one having been relegated in more than 10 years.
The Division 2 competition, from which the winner may challenge for promotion to Premier, has its last round before its semifinals.
Otane, already guaranteed No1 seeding and a home semi-final as they contemplate a possible return Premier rugby - where their last tilt was in the Nash Cup in 2006 - have a bye.
Defending Division 2 champs Aotea, who beat Otane 31-0 a fortnight ago, hope to also bag a home semi when they play fifth-placed Porangahau in Dannevirke.