This year is the first she has not put a team together but Ms Foote said she would still be part of it by joining a group led by her cousin Jude Benson.
The experience was "addictive" for anyone who took part and she encouraged everyone to try it. This will be her ninth year hitting the track.
Through Di's Hair and Wig Specialists, she strives to give people some normality after they lose their hair because of cancer treatments.
"What we try to [do] when they are going through that journey is to help them as much as we can," she said.
Cancer survivors will don sashes for a lap of the course about 2pm on Saturday, setting the tone for 93 teams who take turns to walk or run through the night to raise money for the cause.
Batucada drummers will lead the way in belting out a strong, celebratory beat.
All 1400 participants will be given a purple balloon holding a personal pledge as to how they will try to fight back against cancer - each will be filled with helium and released into the early morning sky on Sunday.
The event has grown substantially in 11 years, with 2015 set to be biggest yet, according to Hawke's Bay Cancer Society manager Trudy Kirk.
Secondary schools made up a large number of those registered this time around, and brought a fresh excitement to the track.
"There will be about 1400 people walking, every team must have a minimum of 10 but most have 20 to 30 and some of the schools have more like 40 in there," Ms Kirk says.
"I think this year there are about 14 teams from schools, they bring a whole different energy - they all compete.
"It's not a race at all but they treat it like one, trying to do more laps and raise more money."
Local entertainers will perform live until 11pm, with quiet recorded music played throughout the evening.
A Property Brokers Relay for Life Charity Auction, held at Hawke's Bay Opera House last Thursday, racked up $25,000 for the Cancer Society to kickstart fundraising.
