Mr Steed said police search and rescue and Hawke's Bay Landsar teams had scoured the large rural property looking for Mrs Wills. The Lowe Corporation rescue helicopter yesterday did an aerial search, but there have been no sightings of the woman.
Police were now appealing to motorists who had travelled on SH5 on Tuesday evening and yesterday who may have seen Mrs Wills in the area. Appeals have also been made to trucking companies who use the highway.
"SH5 is some distance from the farm property, but she may have walked to the highway in a disorientated state. Someone may have picked her up and she may have asked to be taken to another location," Mr Steed said.
Visitors to the 5ha Trelinnoe Gardens over the last few days were also being asked to contact police if they had seen Mrs Wills anywhere on the property during their visits there.
"The property is large and rugged in some parts and we have been extremely thorough in our searches. But unfortunately, there has been absolutely nothing to indicate where Mrs Wills might be. We are hoping someone may have seen her or perhaps picked her up if she did make her way to SH5," Mr Steed said.
Around 30 family friends and neighbours are continuing the search today and search and rescue teams will also be back on the ground.
Anyone who has seen Mrs Wills is urged to contact their nearest police station.