Dr Miller said the uptake of the vaccination had increased each year. Nationally, about 60 per cent of eligible girls took advantage of the free vaccine.
Dr Miller said the safety of the HPV vaccine had been extensively studied around the globe and has been subject to review by a number of international bodies.
"The vaccine was shown to have a good safety profile during large clinical trials involving more than 20,000 people from 30 countries, including New Zealand.
"HPV vaccine is as safe as any of the other vaccines used in our national vaccination schedule," he said.
"It offers a chance to reduce cervical cancers substantially and to reduce the number of cervical abnormalities requiring treatment in the fairly near future. However, that will only happen if the vaccine uptake improves."
Dr Miller said there was plenty of information available to help parents and carers make a decision on whether to offer this vaccination to their daughters.
More than 200,000 girls and young women in New Zealand have had the full three dose course since 2008.