But opener Peter Drysdale was a rock at one end and when Sean Davey arrived at the crease, the fightback began. Davey was the first to three figures, reaching 113 before being caught by Peter Bocock, with the Bay of Plenty captain scoring 118 in a hard-fought knock off 275 balls.
The end came when Bay of Plenty were bowled out for 322 in the 92nd over, to give Hamilton first innings points.
The Bay of Plenty milestones continued to roll on from last weekend's successful Hawke Cup defence. Davey posted his maiden Bay of Plenty century, while it was number three for Drysdale and his highest total in eight seasons of representative cricket. Tony Goodin grabbed a wicket which took his Bay of Plenty total to the 150-wicket mark.
Bay of Plenty have just four days to regroup, before their second Hawke Cup defence against Hawke's Bay starts on Friday.
Fergus Hickey Rosebowl
Hamilton 409/9 declared (Anish Desai 165, Freddy Walker 150no; Sean Davey 5/60, Chris Atkinson 3/117) won on first innings Bay of Plenty 332 (Peter Drysdale 118, Sean Davey 113, Alex Lees 21; James Baker 3/48, Cooper Rowell 3/23, Michael Dodunski 2/44).