A busy Mount Maunganui road is closed following a crash that left two people seriously injured.

A police spokeswoman said the two-car crash happened on Matapihi Rd near the Omanu Golf Course about 7.35am.

A tow truck was dealing with the cleanup, alongside the council.

A St John spokeswoman said two people were taken to Tauranga Hospital with serious injuries.

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A Bay of Plenty District Health Board spokeswoman said a 45-year-old Mt Maunganui woman and a 28-year-old Tauranga man were both in Tauranga Hospital in a stable condition.

Three ambulances had been on the scene.

The police spokeswoman said the road would remain closed as the Serious Crash Unit was heading to the scene to investigate.

Diversions were in place.