Zelda de Villiers will step down from her role as CEO of Dairy Women's Network (DWN) in May 2018.
The organisation will look to recruit a new chief executive in February.
Dairy Women's Network chairwoman Cathy Brown says de Villiers' commercial and financial expertise has led the not-for-profit organisation into a strong position.
"On behalf of the Dairy Women's Network board I'd like to thank Zelda for her leadership over the past four years, and we wish her every success in the future.
"Under her direction, the organisation has solidified its systems, structures and reputation in the industry. We've also grown our membership significantly during her tenure.