Even the Fight of the Century wasn't exempt from an inevitable onslaught of memes, poking fun and ridicule.

Social media erupted with hilarious pictures mocking Conor McGregor after his historic defeat to Floyd Mayweather, the MailOnline reported.

He brutalized McGregor in the 10th round, landing numerous shots and chasing McGregor around the ring until referee Robert Byrd saved the Irishman and stopped the fight.

This Instagram post is a reference to episodes of The Simpsons predicting the future. One foresaw Donald Trump being elected president. Photo / Twitter
This Instagram post is a reference to episodes of The Simpsons predicting the future. One foresaw Donald Trump being elected president. Photo / Twitter
Despite the sportsmanship displayed by each of the fighters one another following the match, the memes targeting McGregor came thick and fast. Photo / Twitter
Despite the sportsmanship displayed by each of the fighters one another following the match, the memes targeting McGregor came thick and fast. Photo / Twitter

Clutching a bottle of his own brand whisky "Notorious", which he said was "coming soon", McGregor appeared to take defeat in his stride during the post-fight press conference.

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"I'm going to take over the Irish whiskey market - and this is delicious!"

He added: "It was a hell of a fight. I would have liked to have seen the end of the 10th.

"I have this patch where I must overcome - I get a little wobbly - but it's more fatigue ... I would have liked to have seen the end of round 10 and seen where it brought us.

This perfectly-time photo shows the moment Mayweather lands a blow on McGregor... that produced some unexpected results. Photo / Twitter
This perfectly-time photo shows the moment Mayweather lands a blow on McGregor... that produced some unexpected results. Photo / Twitter
A mocked-up bromance between the fighters appears to depict them at a tropical lovers' retreat. Photo / Twitter
A mocked-up bromance between the fighters appears to depict them at a tropical lovers' retreat. Photo / Twitter
A nation weeps: One Twitter user took a swipe at Ireland which is no doubt reeling from McGregor's defeat. Photo / Twitter
A nation weeps: One Twitter user took a swipe at Ireland which is no doubt reeling from McGregor's defeat. Photo / Twitter

"You've got to take your hat off to Floyd. It was a good fight. It was a bit of fun, right?"

He added that he thought the referee had done a "great job" despite believing the fight had been called off 'a bit too early', but still respected the decision.

Mayweather said after the fight: "He's a tough competitor. I think we gave the fans what they wanted to see.

"Our game plan was to take our time, let him shoot all his heavy shots early and then take him out at the end down the stretch.

"I gave the fans what they wanted to see. I told them that I owed them for the Pacquiao fight. I must come straight ahead and give them a show."

He then shockingly announced: "I chose the right dance partner for my last dance ... this was my final fight."