Five girls were injured in a single car crash in the Waikato last night.

Waikato Rescue Helicopter crew reported the car had left the road and crashed into a concrete underpass on Lake Arapuni Rd near Waotu, south of Hamilton, at 9.30pm.

The crew flew the injured 17-year-old driver and 15-year-old passenger to Waikato Hospital.

Three others were taken to hospital with minor to moderate injuries by ambulance.