A woman has survived crashing off a Central Otago highway and into Lake Wakatipu this evening.

A police spokeswoman said emergency services were alerted just after 6pm that the woman had crashed off State Highway 6 in the Devils Staircase area.

"[She's] gone into the lake and was trapped ... the driver is out and is speaking with emergency services."

A St John Ambulance spokesman said the woman suffered moderate injuries and would be taken to Lakes District Hospital in Queenstown, which is 35km to the north-west.

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The woman had told emergency services no one else was in the vehicle.

The Coastguard were called to help, but were stood down before arriving at the scene.