When another Twitter user asked if the situation had really happened to the True Blood star, Paquin said, "Yup! Was this some kind of awkward compliment on my possession of a female reproductive system? Or just captain obvious day?"
Paquin, who is known for her roles in vampire drama True Blood and the 1993 Jane Campion film, The Piano, has recently been working on the TV mini-series Roots.
This isn't the first time Paquin has let out her frustration on the social media website. Last week the actress slammed the paparazzi on Twitter for taking photos of her children without her permission, saying that the privacy of her kids had been "violated".
"To be completely clear I'm aware as an actress I have no right to privacy, even on my own property but leave my kids out of it. Nuff said," she wrote.