The restaurant was shutting down for good, not relocating, he said.
Manager of the Strand Arcade, Merv Williams, said the CBD was contracting and feeling a squeeze and Strand tenants had suffered the impact of declining footfall in the CBD and a 6pm closing time for the Arcade.
"It's a reasonably depressed environment," he said.
Eight of the 40 stores at the Strand were vacant but he was confident the departure of McDonald's would not impact the remaining tenants or their view of the Strand.
"We are always concerned but business is a changing environment. You can never be too confident.
"Their business [McDonald's] has changed ... they have a demand for a variety of cafes and a 24-hour operation," he said.
"They want a higher footfall too."
Mr Williams said the Arcade was in negotiations with a potential new tenant, however, he could not comment on the identity of the business.