Northland was more impacted than other regions because most chronic diseases are a culmination of factors with many linked to social deprivation.
"You just need to congratulate yourselves because it is going to be more difficult for you than it will be for other parts of the country," he said.
Dr McKee used examples of how countries in Europe were responding to the increasing burden.
However, he cautioned that just because something was working elsewhere did not necessarily mean it would work here.
Most countries did not spend enough on healthcare, Dr McKee said. What they did spend it on tended to be more on acute care than on chronic diseases.
Northland DHB chief executive Nick Chamberlain said the region had "quite different challenges" to the rest of the country.
Dr McKee, a professor at the London School of Hygiene and Tropical Medicine, has published more than 820 academic papers and 44 books.