He said the NZ Transport Agency was working on solutions for the road.
Earlier he told media the agency was a couple of months away from announcing funding allocations.
Twyford said he appreciated the community's concern and said he was confident the "dangerous" and "neglected" highway would be given high priority.
"State Highway 2 and particularly the northern link is a critical artery that so much new housing development relies on.
"We made safety and reducing deaths and serious injuries the number one goal of our Government's transport policy.
"I expect significant investment in State Highway 2 to better support the urban growth that's happening and to save lives."
Twyford said claims by National MPs that the proposed Tauranga Northern Link highway project had been scrapped was "scaremongering".
He said he expected the Bay of Plenty would be getting a "very significant package of transport projects for the next 10 years".