Traffic was backed up along State Highway 2. Photo / George NovakThe crash was near the intersection of Clarke Rd.
The highway was closed to eastbound traffic for a period but reopened at about 4pm.
A photographer at the scene at about 3pm said traffic was extremely backed up, however, fire trucks at the scene were beginning to leave.
A witness said they heard a "big bang" before people went rushing to help.
Another witness who was driving a few minutes behind described it as a nasty crash.
She said it was a sad sight to see the two people involved, and debris "everywhere".