The Fire Service is managing the safe recovery of the hazardous materials and it is not clear at this stage how long the road will be closed. Further updates will be issued throughout the day.
There are no available detours between Tauranga and Katikati so the alternative for traffic is via the Kaimai Ranges and Matamata.
A second fatal incident happened on State Highway 1, near Putaruru.
A car travelling south away from Putaruru has collided with a truck travelling north. At least one man from the car is dead as a result of that crash.
Police are still trying to ascertain if there were any other people in that vehicle.
Investigations are continuing into both of these crashes and it is too early to say whether either crash was weather related but torrential rain is making road conditions treacherous.
Police are urging all motorists to take extra care. A statement released this morning said: "We've had a long dry summer and the sudden downpour is making roads extremely slippery. As winter fast approaches there is a need to adapt to the changes, slow down and drive to the conditions."
"Police are also urging drivers to give vehicles a winter road check to ensure they are up to standard with roadworthy tyres. Those on two wheels should make sure they are appropriately equipped. Daylight savings increases the need for motorcyclists, mopeds and cyclist to ensure they are visible, have the correct lights on and to wear reflective clothing. Police recommend that you do not cover your reflective clothing with back packs or rain jackets."
Any witnesses to the crash in Rotorua are asked to contact the Rotorua police on (07) 348 0099. Witnesses to the Putaruru crash are asked to contact Tokoroa Police on (07) 885 0100.